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AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1

Adolescents with T1D could benefit from this class of drugs because they tend to have insulin resistance and live with overweight or obesity, and those who develop T1D earlier in life have a greater lifetime risk of long-term complications

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ShimadaKMurayamaTYokodeMKitaTUzuiHUedaTet alN-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production

They also play roles in PANS (Pediatric Acute-onset Neuropsychiatric Syndrome), depression, bipolar disorder, and anxiety disorders

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