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The FDA cited three concerns: potential immunogenicity (the peptide could trigger immune reactions), manufacturing impurity risks (synthetic peptides can contain truncated sequences and other contaminants), and a lack of human safety data sufficient to evaluate risk

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Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation

[6] [4] 4mg) Diarrhoea or constipation Abdominal discomfort and bloating Reduced appetite and early satiety These persistent physical symptoms can understandably affect mood, energy levels, and quality of life, potentially leading to irritability, frustration, or low mood

3 showed that at visit 3, microbiota bacteria relative composition abundance levels were reduced for some taxa while enrichment was observed in other taxonomic families, but returned to similar baseline states in visit 4 and 5

2020;183(5):R14966