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It is important to note that these values may vary according to individuals and specific situations: How can you incorporate vitamin B12 into your daily routine

Oral Forms Efficacy: Injections are generally considered more effective due to direct absorption

Metformin, a medication for individuals with type 2 diabetes mellitus, was found to decrease vitamin B 12 absorption possibly by tying up free calcium required for absorption of the IF-B 12 complex (143)

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Dietary vitamin B12 is bound to proteins in food and must first be released by hydrochloric acid and pepsin in the stomach