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Since many chemotherapeutic agents increase ceramide levels in cells due to increased de novo synthesis of ceramides 66 and CERT1 represents the main exit gate of ceramide from the ER, it is likely that its manipulation will modulate ceramide levels in cells and their response to chemotherapy

By reducing the activity of tyrosinase, arbutin effectively inhibits the production of melanin, thereby reducing dark spots, pigmentation, and overall brightening of the skin tone

Each brain was then placed in a microcentrifuge tube, homogenized in 1.5 mL of formamide using a tissue grinder, and incubated at 60 C for 72 h in a water bath

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Journal reference: Using large language models to assess public perceptions around glucagon-like peptide-1 receptor agonists on social media

Avoid harsh soaps or scrubs that may dry or irritate the skin