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The delayed stomach movement from tirzepatide means ibuprofen stays in contact with the stomach lining longer than usual, increasing irritation risk

Peptides with short half-lives were often dismissed because efficacy could not be sustained, even when acute biological effects were robust

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STAT3 is a key member of the STAT protein family, and its high expression promotes the excessive secretion of inflammatory cytokines and activates CD4 + T cells to aggravate the intestinal inflammatory response

Int Arch Allergy Appl Immunol, 54(2): 171-175