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Focus is placed on mechanisms related to glucose homeostasis, energy expenditure, and lipid metabolism

This iron regulation proves important for preventing brain damage and neuron death

Activated microglia release even more neurotoxic mediators, perpetuating a state of chronic neuroinflammation

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An RCT in 36 patients with type 2 diabetes found that NAC (1,200 mg/day for 4 weeks) combined with a standard diabetes diet significantly reduced fasting glucose, HbA1c, and markers of oxidative stress compared to diet alone (Shahidi et al., J Diabetes Metab Disord, 2020) [56]