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Pipeline of obesity pharmacotherapies GLP-1 receptor agonists GLP-1 RA increase satiety, reduce food intake and delay gastric emptying whilst they also stimulate insulin release and inhibit glucagon secretion in a glucose-dependent manner (Fig

A Satinsky-Debakey vascular clamp was used to atraumatically grasp the superior ridge of the left atrial appendage, a corner of which was encircled with a silk tie and used to retract the appendage

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Some individuals have an immune response to these proteins, leading to inflammation and gut dysbiosis

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