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BDNF supports the survival and function of sensory and motor neurons, and its deficiency contributes to nerve degeneration

In an aging brain, oxidative stress is a major contributing factor to chronic inflammation, leading to cognitive impairment, memory issues, or more serious manifestations

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Nonetheless, the response of NAPstarC mimics the slightly larger response of the NADP + -bound NAPstar and thus NAPstarC represents a useful control for possible pH effects

Glutathione deficiency increases susceptibility to oxidative stress, which may be the underlying cause of many diseases including cancer, heart disease, Parkinsons, and Alzheimers [8]