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Removal of the signal peptide from CzNIS1a abolished this phenotype ( Figure 7B ), complimenting evidence from previous studies that cell death is mediated by apoplastic recognition of the effector by an unknown receptor (Yoshino et al., 2012

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Immunofluorescence Formalin-fixed, paraffin-embedded tissue sections (5 m) were used for immunofluorescence

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This subsequently contributes to the pathophysiological progression of type 2 diabetes, obesity-related metabolic syndrome, and microvascular complications (diabetic nephropathy, retinopathy)