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ClinicalTrials.gov (2016)

However, this is changing

Our products are handled with care, stored under controlled conditions, and reviewed regularly to ensure they meet our standards

Common injection sites used in trials include: The abdomen (at least 5 cm away from the navel) The upper thigh The upper arm (outer aspect) Rotating injection sites with each weekly dose is recommended to reduce the risk of localised skin reactions such as bruising or injection site discomfort

Always monitor heart rate and blood pressure during dose changes of either medication

Clinical trial dosing protocol Phase 2 and Phase 3 trials used a titration approach, starting at lower doses and increasing gradually to minimize gastrointestinal side effects