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These conditions tend to include: underactive thyroid (hypothyroidism) type 2 diabetes menopause Cushing disease polyendocrine metabolic ovarian syndrome (PMOS, formerly PCOS) genetic conditions, like Prader-Willi syndrome If you havent already received a diagnosis, an endocrinologist can determine whether weight gain is from hormonal changes, such as too much or too little of a certain hormone

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A 1% formulation sits within the clinically validated range