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Unfortunately, as mentioned earlier, weight regain is common after discontinuation

If any medication adjustment is recommended, patients should discuss with their endocrinologist or primary care physician: Whether temporary adjustments to other diabetes medications are needed How frequently to monitor blood glucose during this period What glucose levels should prompt contact with the medical team Bowel preparation instructions should be reviewed carefully

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Special Populations Requiring Enhanced Monitoring Patients taking medications that affect heart rate (beta-blockers, calcium channel blockers, digoxin) may require monitoring for cumulative effects on heart rate, though significant pharmacokinetic interactions are uncommon with these agents

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For brand-name medications like Wegovy and Zepbound, fulfillment goes through third-party pharmacies