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Immunohistochemical staining demonstrated partial Cyclin D1 expression, supporting functional activation of the MAPK pathway, whereas no mTOR staining was observed (Figures 2F,G), consistent with the epigenetic findings

Fundoplication surgery mechanically reinforces the lower esophageal sphincter through a surgical procedure

The nuclear factor erythroid 2-related factor 2 (NRF2)/System xc-/GPX4 pathway is regulated by naringenin, which can prevent ferroptosis, and erastin reversed the naringenin-mediated protective effects of cardiomyocytes

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