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Surprisingly, however, in the naked mole-rat, four specific amino acid substitutions in cGAS promote DNA repair and confer a greater capacity to stabilize the genome, counteract cellular senescence and organ aging, and to enhance longevity and health span via evolution ( As described, the cGAS-STING pathway is a canonical in innate inflammatory stress responses, not only within neurons and glial cells of the CNS but also across a broad range of peripheral tissues, contributing to diverse pathological contexts such as cancer (Guo et al., 2025), SARS-CoV-2 infection (Li M

This form is stable, well-tolerated, and easy to take daily

2014, article ID 461591, 9 pages

This course is led by Dr

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