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Experiments conducted by Ahmed and colleagues have shown that pre-treatment of human chondrocytes with EGCG significantly prohibited the activities and expression of MMP-13 and MMP-1 (IC 50 values 16.5 and 27 mM, respectively) in vitro in a dose-dependent manner

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Recent findings demonstrate that TIMP levels change as OA progresses, thus some TIMPs are more crucial in one stage of OA than another [23]

J Mater Chem B

Bai, Y., Gong, X., Dou, C., Cao, Z

Studies that have tested biomarker levels show significant differences between an organic vs