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PLC 2 Phosphatidylinositol-specific phospholipase C gamma 2 (PLC2) has emerged as a significant regulatory enzyme in cellular signaling, primarily through its catalytic role in breaking down membrane-bound phospholipids to produce diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) [157]

mGluRs have eight different subtypes, some of which can be coupled to adenylate cyclase and phospholipase C

[16]Sana S, Ramzan M, et al

Levine, M

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In their study the GSG-Index was found to be elevated in those with NAFLD, more elevated in NAFLD plus obesity, and highly correlated to liver enzymes