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This deficiency is so common that I recommend using B12 for almost all hypothyroid patients regardless of what your labs show

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Curr Gerontol Geriatr Res

That timeline is not arbitrary

Due to its small size and unique copper-binding characteristics, GHK may be able to facilitate rapid exchange of copper in the intracellular space

DOI: Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-16-6866-1 Online ISBN: 978-981-16-6867-8 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)