The study included individuals with diabetes, no prior NAION history, and a semaglutide prescription, comparing them to a control group on nonGLP1 RA antidiabetic medications
For more information, read this article which looks at the connection between thiamine deficiency and small intestinal bacterial overgrowth: When Sibo & Ibs-Constipation Are Just Unrecognized Thiamine Deficiency Thiamine also exerts direct effects on the intestinal barrier
We also dont have strong long-term safety data yet
Crucially, this deficiency strongly correlated with the severity of the patients' fatigue, autonomic dysfunction, and neurocognitive symptoms
Complement-containing small extracellular vesicles from adventitial fibroblasts induce proinflammatory and metabolic reprogramming in macrophages
Location Back Bay, Boston, MA Areas We Serve Boston, MA Back Bay, MA Beacon Hill, MA South End, MA North End, MA Fenway-Kenmore, MA Charlestown, MA Dorchester, MA Jamaica Plain, MA Allston, MA Brighton, MA West Roxbury, MA Roslindale, MA East Boston, MA South Boston, MA Mission Hill, MA Hyde Park, MA Mattapan, MA Seaport, MA Somerville, MA Compounded versions of tirzepatide/semaglutide are not FDA-approved, and neither the FDA nor any global regulatory agency has reviewed these products for safety, quality, or efficacy.
