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Next to indole, which acts on voltage-gated K + channels to enhance Ca 2+ entry thereby stimulating GLP-1 secretion (36) and microbiota-derived SCFA that are sensed by FFAR2/GPR43 and FFAR3/GPR41 (see above), the importance of bile acid-induced incretin secretion via the bile acid receptor GPBAR/TGR5 has been proven in vitro and in vivo

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Fruit juices, even freshly pressed, bypass the fiber that slows sugar absorption and can cause rapid glucose spikes followed by energy crashes

Conflict of Interest DDDL is named as an inventor in patent USA Patent Number 9,616,108, 2017