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Canonical Wnt/-catenin signaling pathway is activated via increased production of Wnt ligands by NTAPP To investigate whether NTAPP exposure affect a biological response via the canonical Wnt/-catenin signaling pathway, we treated hDP cells with two types of pharmacological inhibitor of Wnt/-catenin signaling, endo-IWR1 25 and IWP2 26 before NTAPP treatment

10.1186/s12974-022-02511-0 31 DingZ.YangC.ZhaiX.XiaY.LiuJ.YuM

Jiang SQ, Huang QF, Xie WM, Lv C, Quan XQ

Triple agonists including retatrutide show exceptional promise based on remarkable weight loss and liver fat normalization in early trials, with dedicated MASH histology studies ongoing

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