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If you experience consistent weekly weight loss, stable appetite suppression, and good tolerability at 0.5 mg, 1.0 mg, or 1.7 mg, there is no clinical reason to escalate further

Lorsbach BA, Sparks TC, Cicchillo RM, Garizi NV, Hahn DR, Meyer KG

Most patients report appetite reduction by day 37, but meaningful scale movement typically begins between weeks 2 and 4

Diet as a Risk Factor for Rheumatoid Arthritis

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Eur J Endocrinol 176:685693 [DOI] [PMC free article] [PubMed] [Google Scholar] 39.Khalid SI, Omotosho PA, Spagnoli A, Torquati A (2020) Association of Bariatric Surgery With Risk of Fracture in Patients With Severe Obesity