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The immediate priority is to address the drug delivery challenge

GEP44 activates insulin-independent glucose uptake in muscle tissue via its interactions with Y1-R Despite the positive ISR data and hypothesis that GEP12 would prove superior to GEP44, we noted in in vivo studies (vide infra) that it was considerably inferior to GEP44 in terms of food intake and body weight reduction

D., Daubioul, C

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Medicine and Science in Sports and Exercise

Retatrutide (LY3437943) is an investigational peptide studied for interaction with three receptor pathways: GLP-1, GIP, and glucagon receptors