The EGR-1/NAB2 feedback regulatory loop appears to create self-sustaining repair programs, explaining why effects continue well after administration stops
Jason LA, McGarrigle WJ, Vermeulen RCW
61 In a trial of 52 iron-deficient children on methylphenidate randomized to receive iron supplementation (ferrous sulfate 300 mg capsule containing 80 mg of elemental iron) or placebo for 12 weeks, parents reported significant improvement in ADHD symptoms for those receiving iron but not for those receiving placebo
It's a 15-amino acid chain: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Asp Classification : Pentadecapeptide (15 amino acids) Origin : Derived from gastric cytoprotective compounds Primary targets : Tissue repair, angiogenesis, growth factor upregulation Primary use : Tendon, ligament, and connective tissue repair Why Tendon Repair Is Challenging Tendons have notoriously poor blood supply compared to muscle
However, inflammation is also necessary (in short bursts) to fight things like infectious invaders
Figure 1 ) reversed a number of age-related changes in liver mitochondrial function yet increased liver mitochondrial oxidant production (18)
