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BYSTANDER EFFECT Influence of a drug on untargeted cells, in the present context by diffusion of an activated cytotoxin from hypoxic cells to surrounding cells at higher oxygen concentrations

Protein expression We used the Bac-to-Bac baculovirus system (Thermo Fisher) in Spodoptera frugiperda ( sf9 ) cells for expression

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After the first session, the Glutax 600gs Ultrafiltration Injection takes a maximum of 30 minutes

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This does not invalidate the findings but adds a potential source of bias Single-blind only: While the investigator assessing photos was blinded, patients knew whether they received the active serum or saline, which could influence self-reported satisfaction scores No long-term follow-up: The study ended at 6 months