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These reports allow the FDA to assess the impact of counterfeit medications, identify potential dangers not found during standard regulatory processes, and take appropriate actions to protect public health

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These findings link previously reported robust clinical outcomes with underlying biochemical mechanisms, although the post-hoc exploratory analysis remains hypothesis-generating and does not prove causality

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Among the 53 SLC25 proteins in human, the most well-characterized ones include adenine nucleotide carriers (ANTs) that exchange ADP for ATP to support cellular bioenergetics and UCP1 that is exclusively expressed in brown adipose tissue and dissipates proton motive force to generate heat