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10.1124/jpet.105.093286 27 MaioneS.RadanovaL.De GregorioD.LuongoL.De PetrocellisL.Di MarzoV.et al (2015)

These salient effects were inhibited by nicotinamide (Fig

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Moreover, the apoptosis and depletion of Lgr5+ intestinal epithelial stem cells impairs epithelial regeneration, whereas the dysregulation of the Wnt/-catenin signaling pathway hinders mucosal repair 67