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10.1016/j.bcp.2023.115613 88 MantovaniA.PetraccaG.BeatriceG.CsermelyA.LonardoA.TargherG

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Diabetes Care 41 , e133e135 (2018)

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The combination creates a dual mechanism: naltrexone reduces food reward and craving intensity, while bupropion enhances the brain's satiety signals and provides mild stimulant-like appetite suppression

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