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pointed out that in vivo and in vitro experiments, heat stress can ultimately induce hepatocyte pyroptosis by mediating the activation of the HMGB1 signaling pathway [26]

This has been confirmed by other authors [39]

It plays a crucial role in protecting cells from oxidative stress caused by environmental pollutants, UV radiation, toxins, and ageing

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has been tested ELISA and Western blot analysis to assure specificity and reactivity

In 2017, a post hoc pooled analysis of RCTs on liraglutide demonstrated comparably low incidences of depression and anxiety in both the liraglutide and placebo cohorts