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A 2024 review from the University of Illinois Chicago Drug Information Group, which summarizes recommendations from multiple clinical guidelines, notes that many experts recommend continuing naltrexone for at least 3 to 6 months, with longer treatment individualized based on a persons response and goals

Its definitely possible that with the opening up of more indications, theres going to be a higher demand and subsequent future shortages. With fallout from the tirzepatide shortage still ongoing and the compounded semaglutide deadlines fast approaching, it remains to be seen how, and indeed if, the FDA will enforce its legislation.

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