10.1007/s12026-013-8384-0 4 AnsariM
Because LaccID does not require H 2 O 2 and its activity is inherently selective for the cell surface (obviating the need for special probes such as BxxP), we wondered whether LaccID could be used for nontoxic mapping of cell-type-specific surfaceomes in complex biological settings
Both of these occur inside mitochondria
Serum Trp and Kyn levels were determined using an HPLC with mass spectrometric detection method as described previously [22], and 5-HT levels were determined using HPLC-electrochemical detection [23]
An increase in iron content switches Fas from being an anti-apoptotic protein to being a pro-apoptotic protein, thereby activating the extrinsic apoptosis pathway and promoting necroptosis [91]
134 Aged mice show a decrease in the reconstitution capability of their hematopoietic stem cells (HSCs), correlating with an increase in DNA damage 135,136 and with an increase in the levels of senescence effectors, such as p16INK4a
