94 As previously described, a controlled trial found 20 mg CoQ10 three times daily, when combined with 1 gram L-carnitine twice daily, resulted in a higher pregnancy rate than either supplement alone or placebo in 262 men with infertility and abnormal semen analyses
Clinical trials tested doses ranging from 250mcg to 1mg daily, with most protocols settling around 300-500mcg for optimal fat metabolism support
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For long-term studies, this can sometimes present practical challenges, especially if high frequency of administration is required
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the pharmacokinetics are not