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This usually requires the addition of an activating reagent such as dimethylaminopropanol (DMA) or tetrahydrofuran alcohol (THF)

The glucagon component adds three distinct mechanisms: increased hepatic energy expenditure and thermogenesis (increasing resting metabolic rate by an estimated 100-200 kcal/day), enhanced hepatic fatty acid beta-oxidation (directly reducing liver fat), and lipolysis in both hepatic and adipose tissue

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Talking With Patients About Alcohol and GLP1s Effective patient communication is essential when discussing GLP-1 alcohol use reduction

doi:10.1007/s11010-023-04736-w 58

Yu MH, Lee JM, Baek JH, Han JK, Choi BI