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The decision follows U.S

Regardless of having a sulfa allergy or not, it is always important to discuss risks and benefits with a doctor before starting any medication

Activation of the GLP-1 receptor (GLP-1R) by GLP-1 stimulates insulin release and inhibits glucagon secretion in a glucose-dependent manner ( 4 )

A similar drug called tirzepatide (Zepbound) was approved by the FDA in December 2024 to treat sleep apnea in people with a BMI of 30 or higher

It slows down how quickly your stomach empties, which keeps you feeling full longer, and it acts on your brain to reduce appetite and cravings

If you want simplicity and established evidence, tirzepatide monotherapy remains the safer, better-documented choice