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The mechanistic rationale is well established across preclinical and translational models, and a growing body of randomized trial and meta-analytic evidence supports the possibility of meaningful improvements in glycemic and inflammatory outcomes in appropriately selected patient groups

Next-generation compounds aim to selectively activate the Gq pathway while minimizing beta-arrestin recruitment

2013;8(11):e74883

Increasing evidence indicates that patients with FSGS exhibit gut microbial dysbiosis [146]

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L-carnitine is an amino acid compound that is formed in the liver from individual amino acids as needed