Signs & Symptoms Fatigue, weakness Swelling (edema) in legs, face Decreased urine output (oliguria/anuria) or sometimes polyuria in early CKD Nausea, vomiting, anorexia Shortness of breath (due to fluid overload) Confusion (from uremia) High blood pressure Itchy skin (uremic pruritus) Complications Electrolyte imbalance ( potassium arrhythmias) Metabolic acidosis Anemia ( erythropoietin) Bone disease (due to calcium-phosphate imbalance, vitamin D activation) Cardiovascular disease Management AKI: Treat underlying cause (e.g., fluids for dehydration, relieve obstruction, stop nephrotoxic drugs)
Fewer injections Compared to basal-bolus therapy, taking an insulin/GLP-1 combination drug substantially reduces the number of daily insulin injections you need
Humans are the only natural hosts
Instead, use a new Repatha dose
Ready-to-use- food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial
Zhou C, Li X, Wang C, Zhang J
