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While she was taking many medications, she noted that for the past year she had also been taking semaglutide, a GLP-1 weight-loss drug, and had lost about 40 pounds (over 19 percent of her body weight)

Dehydration disrupts electrolyte balance, increasing cramp risk

doi: 10.1016/j.bonr.2017.11.001 90 KoFCJochumSBWilsonBMAdraAPatelNLeeHet al

In a double blind, dosing range study, the group that used topic malassezin twice a day for 8 weeks had a 30.13% reduction in the severity of hyperpigmentation, compared with 16.67% in the placebo group

The reason this matters: many patients who 'plateau' on GLP-1 medications like semaglutide or tirzepatide despite appetite suppression are dealing with impaired hepatic lipid export

86 Some evidence suggests individuals with MTHFR polymorphisms may need higher doses of folic acid to experience therapeutic benefits and may respond better to supplementation with 5-methyltetrahydrofolate (5-MTHF), the active form of this B vitamin