The extensive physiological and behavioral effects of GLP-1 are mediated by the GLP-1 receptors (GLP-1R), which are expressed in both the central and autonomic nervous systems (Merchenthaler et al., 1999
[8] Writing Committee Members et al
And the research, while promising, comes with important limitations that most guides conveniently ignore
The naming follows the progression researchers and writers have used to describe the metabolic peptide field's evolution: GLP-1 (single receptor agonist like semaglutide), then dual agonist (GLP-1 + GIP, like tirzepatide), and now what some refer to as "GLP-3" (triple agonist activating GLP-1, GIP, and glucagon receptors, like retatrutide)
Your provider may recommend a series of injections over a few weeks for optimal outcomes
Data Availability The datasets used and analyzed during the current study are available from the corresponding author on reasonable request