After expiry, semaglutide may undergo chemical degradation through hydrolysis, oxidation, or deamidation, reducing the concentration of active ingredient and potentially rendering the medication less effective or inactive
Marso SP, Baeres FMM, Bain SC, Goldman B, Husain M, Nauck MA, Poulter NR, Pratley RE, Thomsen AB, Buse JB, et al
Lifetime body mass index, other anthropometric measures of obesity and risk of knee or hip osteoarthritis in the GOAL case-control study
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One possible mechanism by which semaglutide may improve thyroid function is through its effects on the gut microbiome
Wu CX, Zhang SA, Liu MD, He JH