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Semaglutide monotherapy typical starter doses range from 0.25 mg to 0.5 mg, whereas tirzepatide's microdose range often sits at 1.25 mg to 2.5 mg

New-onset proliferative diabetic retinopathy (PDR) (grade R3M0, R3M1) occurred in 1.1% of tirzepatide-exposed ( n =33) and 0.5% of tirzepatide-unexposed ( n =17) individuals

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These are not wonder drugs that will fix everything that is wrong with us, and thats why we have to do the clinical trials, and we need rigorous evidence, Drucker says, adding that Novo Nordisk deserves credit for doing the trials despite the low odds of success