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This was achieved by Novo Nordisk with semaglutide, marketed as Ozempic for diabetes and Wegovy for obesity

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Wegovy is intended to be a long-term medication

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An MPO inhibitor, when applied in the MSA mouse model in the early stage of the disease, suppressed microglial activation and neuroinflammation, reduced intracellular aggregates of -syn, and rescued neuronal loss and improved motor deficits