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Most of our understanding of this multistep pathway stems from studies in yeast and bacteria, where the sequential actions of these enzymes have been genetically and biochemically dissected 28,33
Reduccin gradual de dosis: Algunos clnicos exploran la posibilidad de reducir gradualmente la dosis a la mnima efectiva en lugar de suspender completamente el medicamento
2025, www.accessdata.fda.gov/drugsatfda_docs/label/2025/215256s024lbl.pdf
However, the risks far outweigh any potential benefit of saving the dose
Gradual drug titration can mitigate central nervous system side effects by allowing the body to develop pharmacodynamic tolerance [44]
10.1016/j.nlm.2016.07.012 34
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