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This review will outline the physiology and pharmacological potential of amylin and GLP-1, respectively, and focus on innovative peptide drug development leading to drugs acting on two or more distinct receptors, such as an amylin and GLP-1 peptide hybrid, potentially producing a more effective treatment strategy to combat the rapidly increasing global obesity

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[DOI] [PubMed] [Google Scholar] 129.Lingvay I., Deanfield J., Kahn S.E., Weeke P.E., Toplak H., Scirica B.M., Rydn L., Rathor N., Plutzky J., Morales C., et al

In the present study, supplementation with vitamin B12 did not significantly improve the markers of glucose metabolism

Roles of insulin-like growth factor-I and growth hormone in mediating insulin resistance in acromegaly

Other studies developed its application as a laboratory reagent to probe peptidemediated signaling process related to tissue homeostasis, angiogenic signaling, and cellular stress response in vitro/ preclinical conditions