tirzepatide not losing weight reddit for the Maintenance of Body Reduction: Rationale, Design, and Baseline Characteristics of SURMOUNT‐MAINTAIN - Horn - 2025 - Obesity Why Is Tirzepatide Not Working

We previously offered tirzepatide

Previously, 2.4mg Semaglutide injection lost 15.8% of weight at 68 weeks (STEP-8 trial)

The primary outcome measured clinical response by MS at Week 8, with secondary outcomes including clinical remission, mucosal healing, quality of life measures, and safety assessments through Week 17

In the future, the effect can be enhanced by optimizing the delivery system (such as nanocarriers, microneedle technology) or combining treatment regimens

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Oral formulations are also available for patients who prefer pills over injections, though they require higher doses to achieve comparable absorption