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Ample evidence shows dysbiosis of gut microbiota in AKI and CKD, such as diabetic kidney disease (DKD), membranous nephropathy (MN), immunoglobulin A nephropathy (IgAN), focal segmental glomerulosclerosis (FSGS), hypertensive nephropathy (HN), and lupus nephritis (LN), as well as renal replacement therapies including peritoneal dialysis (PD), hemodialysis (HD), and kidney transplantation [24, 33-38]