For example, conditions such as thyroid disorders , polycystic ovary syndrome (PCOS) , and insulin resistance can affect how well these medications manage appetite and metabolism
Administered as a once-weekly injection, Wegovy is indicated for adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition
In the agent-level analysis, tirzepatide reduced MACE compared to placebo (HR 0.81, 95% CI 0.700.94) and lixisenatide (HR 0.79, 95% CI 0.650.97)
While the surging popularity of semaglutide for general weight loss has the potential to spur a long-term shortage for people who need the drug for its intended purposes (like for type 2 diabetes), raising a murky conversation about ethics, those looking to lose weight can take the drugs should they get a prescription
The choice matters
Topiramate may help with weight loss in a few ways