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Furthermore, many patients prescribed tirzepatide for type 2 diabetes are concurrently taking metformin, which independently increases the risk of vitamin B12 deficiency through impaired calcium-dependent B12-intrinsic factor uptake in the ileum

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It is a well-known fact that maintaining optimal brain health is essential for normal cognitive function, memory, and overall mental and physical well-being

Ali MRK, Wu Y, Tang Y, Xiao H, Chen K, Han T, et al

What is largely agreed on, however, is that B12 deficiency can reduce energy levels and therefore make it harder to stay active and maintain a healthy weight

Other Drugs That Affect Vitamin B12: The diabetes medicine Glucophage (metformin) can also lead to problems with vitamin B12