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Intriguingly, genetic variations with reduced IIS due to SNPs of interacting components of the IIS cascades ( GH1, IGF1, IGF1R, IRS1, FoxO1A, FoxO3A ) and have been associated with increased longevity [30, 31]

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Ive been trudging through a multitude of interrelated health and hormonal issues since I was a teen, and while Ive seen over 2 dozen doctors for these particular issues, nobody nobody