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The FDA prescribing information for Wegovy (semaglutide) reports musculoskeletal painincluding back pain and extremity painas possible side effects, as does the prescribing information for Zepbound (tirzepatide)
However, it remains unclear whether GLP-1 therapy would provide meaningful clinical benefit for RA-specific outcomes such as joint damage progression, functional status, or quality of life in patients without concurrent diabetes or obesity
doi: 10.3389/fimmu.2018.02648 86 Rosas-BallinaMGoldsteinRSGallowitsch-PuertaMYangLValdes-FerrerSIPatelNBet al
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