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Genetic Factors in GLP-1 Tolerance and Digestive Side Effects Individual variations in how your body processes and responds to GLP-1 medications are partly determined by your genetic makeup, particularly genes controlling GLP-1 receptor function, appetite signaling, and gastrointestinal motility

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Special Situations & High-Risk Groups Immunocompromised patients No direct immunosuppression

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Wilsman NJ

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Adverse effect management : Educate patients about expected gastrointestinal effects and when to seek medical attention