124 Additionally, both CBS and CSE can catalyze -substitution reactions, resulting in the condensation of two L-Cys molecules to produce H 2 S and lanthionine, or the condensation of L-Hcy and L-Cys through , -substitution reactions to produce H 2 S and cystathionine
Although it has a powerful physiological function, more studies have focused on its pathological role, mainly because it is involved in the pathogenesis of several neurodegenerative diseases, such as Parkinsons disease (PD) and dementia of Lewy body (DLB) [7, 8]
NAC is widely studied, but the evidence depends on the population, dose, route, outcome and product
The labeling efficiencies of the CreER lines used here were very high
Karimi Zarchi AA, Faramarzi MA, Gilani K, Ghazi-Khansari M, Ghamami G, Amani A
Enhanced activation of mTOR leads to an increase in the phosphorylation of proteins downstream of mTORC1, such as S6 kinase (S6K) and eIF4E-binding proteins (4E-BPs), thereby promoting cap-dependent protein translation (66, 67)
